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Kyung Lib Jang Selected Research

Checkpoint Kinase 2

11/2019HBx natural variants containing Ser-101 instead of Pro-101 evade ubiquitin-dependent proteasomal degradation by activating proteasomal activator 28 gamma expression.
7/2017Hepatitis B virus X protein activates E3 ubiquitin ligase Siah-1 to control virus propagation via a negative feedback loop.
1/2017Hepatitis C virus core activates proteasomal activator 28γ expression via upregulation of p53 levels to control virus propagation.

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Kyung Lib Jang Research Topics

Disease

15Hepatocellular Carcinoma (Hepatoma)
07/2022 - 11/2002
14Neoplasms (Cancer)
06/2015 - 10/2004
6Infections
07/2022 - 04/2014
6Carcinogenesis
01/2021 - 06/2003
4Ataxia Telangiectasia (Louis Bar Syndrome)
12/2021 - 01/2017
3Neoplasm Metastasis (Metastasis)
06/2015 - 02/2007
2Carcinoma (Carcinomatosis)
09/2012 - 02/2007
1Coinfection
12/2021
1Persistent Infection
01/2017
1Inflammation (Inflammations)
04/2015
1Prostatic Neoplasms (Prostate Cancer)
07/2010
1Nasopharyngeal Carcinoma
10/2008
1Hypoxia (Hypoxemia)
10/2006
1Lymphoma (Lymphomas)
12/2005
1Burkitt Lymphoma (Burkitt's Lymphoma)
12/2005

Drug/Important Bio-Agent (IBA)

13Proteins (Proteins, Gene)FDA Link
07/2022 - 12/2005
7Cadherins (E-Cadherin)IBA
07/2022 - 10/2005
7Tretinoin (Retinoic Acid)FDA LinkGeneric
10/2017 - 10/2008
5hepatitis B virus X proteinIBA
07/2022 - 11/2002
3Checkpoint Kinase 2IBA
11/2019 - 01/2017
3Biological ProductsIBA
02/2010 - 06/2007
2Reactive Oxygen Species (Oxygen Radicals)IBA
12/2021 - 11/2019
2Phosphotransferases (Kinase)IBA
12/2021 - 07/2017
2Proteasome Endopeptidase Complex (Proteasome)IBA
01/2021 - 01/2020
2UbiquitinIBA
01/2020 - 12/2005
2Vitamin A (Retinol)FDA LinkGeneric
10/2017 - 06/2015
2Cell Adhesion MoleculesIBA
03/2008 - 10/2005
2beta CateninIBA
08/2007 - 12/2005
2Membrane Proteins (Integral Membrane Proteins)IBA
10/2006 - 12/2005
21-dodecylpyridoxal (PLD)IBA
10/2004 - 06/2003
1DNA (Deoxyribonucleic Acid)IBA
04/2014
1MethyltransferasesIBA
04/2014
1Pharmaceutical PreparationsIBA
09/2011
1hydrogen sulfite (bisulfite)IBA
07/2010
1Biomarkers (Surrogate Marker)IBA
02/2010
1beta-Galactosidase (Lactaid)IBA
02/2010
1RetinoidsIBA
10/2008
1A-factor (Streptomyces)IBA
02/2007
1Glycoproteins (Glycoprotein)IBA
02/2007
1Mucin-1 (CA 15-3 Antigen)IBA
02/2007
1Prolyl Hydroxylases (Prolyl Hydroxylase)IBA
10/2006
1Hypoxia-Inducible Factor 1IBA
10/2006
1Ligases (Synthetase)IBA
12/2005
1Oncogene Proteins (Oncogene Protein)IBA
12/2005
1Glycogen Synthase KinasesIBA
12/2005
1RNA (Ribonucleic Acid)IBA
12/2005
1Phospholipase DIBA
10/2004
1IsoenzymesIBA
06/2003

Therapy/Procedure

1Therapeutics
09/2011